414 Results for "

Acer saccharum Marshall

" in MedChemExpress (MCE) Product Catalog:
Products (414)

414 Results for "Acer saccharum Marshall" in MCE Product Catalog:

39
Emodin
Emodin
0 Images
39 Publications Verification
Cat. No.: HY-14393
CAS No.: 518-82-1
Purity:  99.25%
Synonyms: Frangula emodin
Category:  

Polygonaceae Plants Endogenous metabolite Quinones Human Gut Microbiota Metabolites Microorganisms Rheum palmatum L. Anthraquinones Phenols Polyphenols Disease Research Fields Cancer

Target:  

SARS-CoV Casein Kinase Autophagy 11β-HSD

Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction . Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects . Emodin is a potent selective 11β-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice .
39
Emodin (Standard)
Emodin (Standard)
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39 Publications Verification
Cat. No.: HY-14393R
CAS No.: 518-82-1
Synonyms: Frangula emodin (Standard)
Category:  

Quinones Rheum palmatum L. Polygonaceae Phenols Plants Disease Research Fields Cancer

Target:  

Reference Standards SARS-CoV Casein Kinase Autophagy 11β-HSD

Emodin (Standard) is the analytical standard of Emodin. This product is intended for research and analytical applications. Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction . Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects . Emodin is a potent selective 11β-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice .
26
Ursodeoxycholic acid
Ursodeoxycholic acid
0 Images
26 Cited Publications
Cat. No.: HY-13771
CAS No.: 128-13-2
Purity:  99.94%
Synonyms: Ursodeoxycholate; Ursodiol; UDCA
Category:  

Human Gut Microbiota Metabolites Other disease Disease markers Endogenous metabolite Disease Research Fields Cancer Steroids

Target:  

G protein-coupled Bile Acid Receptor 1 FXR Angiotensin-converting Enzyme (ACE) Endogenous Metabolite

Ursodeoxycholic acid (Ursodeoxycholate) is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Ursodeoxycholic acid also reduces ACE2 expression and is beneficial for reducing SARS-CoV-2 infection. Orally active .
25
MLN-4760
MLN-4760
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25 Cited Publications
Cat. No.: HY-19414
CAS No.: 305335-31-3
Target:  

Angiotensin-converting Enzyme (ACE)

연구분야:  

Cardiovascular Disease

MLN-4760 is a potent and selective human ACE2 inhibitor (IC50, 0.44 nM), with excellent selectivity (>5000-fold) versus related enzymes including human testicular ACE (IC50, >100 μM) and bovine carboxypeptidase A (CPDA; IC50, 27 μM).
23
Captopril
Captopril
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23 Cited Publications
Cat. No.: HY-B0368
CAS No.: 62571-86-2
Synonyms: SQ 14225
Target:  

Angiotensin-converting Enzyme (ACE)

연구분야:  

Cardiovascular Disease Cancer

Captopril (SQ 14225), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM) and has been widely used for research of hypertension and congestive heart failure. Captopril is also a New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with an IC50 of 7.9 μM .
19
Methylprednisolone
Methylprednisolone
0 Images
19 Cited Publications
Cat. No.: HY-B0260
CAS No.: 83-43-2
Synonyms: U 7532
Target:  

Glucocorticoid Receptor Autophagy SARS-CoV Bacterial

연구분야:  

Cardiovascular Disease Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer

Methylprednisolone (U 7532) is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties. Methylprednisolone improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels .
19
Methylprednisolone (Standard)
Methylprednisolone (Standard)
0 Images
19 Cited Publications
Cat. No.: HY-B0260R
CAS No.: 83-43-2
Synonyms: U 7532 (Standard)
Target:  

Reference Standards Glucocorticoid Receptor Autophagy SARS-CoV Bacterial

연구분야:  

Infection Inflammation/Immunology Endocrinology Cancer

Methylprednisolone (Standard) is the analytical standard of Methylprednisolone. This product is intended for research and analytical applications. Methylprednisolone is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties. Methylprednisolone improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels .
17
Talfirastide acetate
Talfirastide acetate
0 Images
17 Cited Publications
Cat. No.: HY-12403A
CAS No.: 2855063-75-9
Purity:  99.87%
Synonyms: TXA127 acetate; Angiotensin (1-7) acetate; Ang-(1-7) acetate
Category:  

Natural Products Endogenous metabolite Disease Research Fields Inflammation/Immunology Endocrinology

Target:  

Angiotensin Receptor Angiotensin-converting Enzyme (ACE) Endogenous Metabolite

Angiotensin 1-7 (Ang-(1-7)) acetate is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 acetate inhibits purified canine ACE activity (IC50=0.65 μM). Angiotensin 1-7 acetate acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 acetate blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium .
17
Talfirastide
Talfirastide
0 Images
17 Cited Publications
Cat. No.: HY-12403
CAS No.: 51833-78-4
Purity:  99.75%
Synonyms: TXA127; Angiotensin (1-7); Ang-(1-7)
Category:  

Natural Products Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:  

Angiotensin Receptor Angiotensin-converting Enzyme (ACE) Endogenous Metabolite

Angiotensin 1-7 (Ang-(1-7)) is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 inhibits purified canine ACE activity (IC50=0.65 μM). Angiotensin 1-7 acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium. Angiotensin 1-7 shows anti-inflammatory activity .
13
Enalapril
Enalapril
0 Images
13 Cited Publications
Cat. No.: HY-B0331
CAS No.: 75847-73-3
Synonyms: MK-421
Target:  

Angiotensin-converting Enzyme (ACE)

연구분야:  

Cardiovascular Disease Cancer

Enalapril (MK-421) is an angiotensin-converting enzyme (ACE) inhibitor, can be used for hypertensive diseases research .
13
Enalapril maleate
Enalapril maleate
0 Images
13 Cited Publications
Cat. No.: HY-B0331A
CAS No.: 76095-16-4
Synonyms: MK-421 maleate
Target:  

Angiotensin-converting Enzyme (ACE)

연구분야:  

Cardiovascular Disease Cancer

Enalapril (MK-421) maleate, the active metabolite of enalapril, is an angiotensin-converting enzyme (ACE) inhibitor.
11
Diminazene aceturate
Diminazene aceturate
0 Images
11 Cited Publications
Cat. No.: HY-12404
CAS No.: 908-54-3
Purity:  99.16%
Synonyms: Diminazene diaceturate
Target:  

Parasite Angiotensin-converting Enzyme (ACE)

연구분야:  

Infection Inflammation/Immunology

Diminazene aceturate (Diminazene diaceturate) is an anti-trypanosome agent for livestock. The main biochemical mechanism of the trypanocidal actions of Diminazene aceturate is by binding to trypanosomal kinetoplast DNA (kDNA) in a non-intercalative manner through specific interaction with sites rich in adenine-thymine base pairs. Diminazene aceturate is also an angiotensin-converting enzyme 2 (ACE2) activator and has strong and potent anti-inflammatory properties .
8
Vicenin 2
Vicenin 2
0 Images
8 Cited Publications
Cat. No.: HY-N2165
CAS No.: 23666-13-9
Category:  

Cardiovascular Disease Flavonoids Leguminosae Flavones Phenols Polyphenols Plants Disease Research Fields Desmodium styracifolium (Osbeck.) Merr.

Target:  

Angiotensin-converting Enzyme (ACE)

Vicenin 2, a flavonoid, is an orally active angiotensin-converting enzyme (ACE) inhibitor (IC50 of 43.83 μM) . Vicenin 2 has radioprotective, anti-nociceptive effects, anti-glycation anti-inflammatory, antioxidant, anticancer, antiangiogenic properties .
6
(Z)-Guggulsterone
(Z)-Guggulsterone
0 Images
6 Cited Publications
Cat. No.: HY-110066
CAS No.: 39025-23-5
Purity:  99.30%
Category:  

Commiphora myrrha (Nees) Engl. Plants Burseraceae Disease Research Fields Cancer Steroids

Target:  

Apoptosis VEGFR Akt Angiotensin-converting Enzyme (ACE) SARS-CoV FXR

(Z)-Guggulsterone, a constituent of Indian Ayurvedic medicinal plant Commiphora mukul, inhibits the growth of human prostate cancer cells by causing apoptosis. (Z)-Guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis . (Z)-Guggulsterone is also a potent FXR antagonist. (Z)-Guggulsterone reduces ACE2 expression and SARS-CoV-2 infection .
5
Luspatercept
Luspatercept
0 Images
5 Cited Publications
Cat. No.: HY-P99720
CAS No.: 1373715-00-4
Synonyms: ACE-536; luspatercept–aamt

Target:  

TGF-beta/Smad

연구분야:  

Metabolic Disease Cancer

Luspatercept (ACE-536) is a recombinant modified ActRIIB fusion protein that binds with transforming growth factor β superfamily ligands. Luspatercept increases the erythrocyte numbers and promotes maturation of erythroid precursors. Luspatercept binds with GDF11 and inhibits Smad2/3 signaling. Luspatercept can be used for the research of anemia .
5
Sinapinic acid
Sinapinic acid
0 Images
5 Cited Publications
Cat. No.: HY-W009732
CAS No.: 530-59-6
Synonyms: Sinapic acid
Category:  

other families Monophenols Simple Phenylpropanols Metabolic Disease Phenols Phenylpropanoids Plants Disease Research Fields

Target:  

HDAC Angiotensin-converting Enzyme (ACE) Reactive Oxygen Species (ROS) Apoptosis

Sinapinic acid (Sinapic acid) is a phenolic compound isolated from Hydnophytum formicarum Jack. Rhizome, acts as an inhibitor of HDAC, with an IC50 of 2.27 mM , and also inhibits ACE-I activity . Sinapinic acid posssess potent anti-tumor activity, induces apoptosis of tumor cells . Sinapinic acid shows antioxidant and antidiabetic activities . Sinapinic acid reduces total cholesterol, triglyceride, and HOMA-IR index, and also normalizes some serum parameters of antioxidative abilities and oxidative damage in ovariectomized rats .
3
Fosinopril sodium
Fosinopril sodium
0 Images
3 Cited Publications
Cat. No.: HY-B0382
CAS No.: 88889-14-9
Synonyms: SQ28555
Target:  

Angiotensin-converting Enzyme (ACE) Apoptosis

연구분야:  

Cardiovascular Disease

Fosinopril Sodium is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension and some types of chronic heart failure.
3
Peimisine
Peimisine
0 Images
3 Cited Publications
Cat. No.: HY-N0214
CAS No.: 19773-24-1
Synonyms: Ebeiensine
Category:  

Alkaloids Piperidine Alkaloids Liliaceae Plants Disease Research Fields Inflammation/Immunology Fritillaria cirrhosa

Target:  

mAChR Angiotensin-converting Enzyme (ACE) Apoptosis

Peimisine (Ebeiensine) is a muscarinic M receptor antagonist and angiotensin converting enzyme (ACE) inhibitor. Peimisine shows anti-tumor, anti-inflammatory, antihypertensive activities. Peimisine can induce apoptosis and be used in cough and asthma research .
3
Peimisine hydrochloride
Peimisine hydrochloride
0 Images
3 Cited Publications
Cat. No.: HY-N0214A
CAS No.: 900498-44-4
Synonyms: Ebeiensine hydrochloride
Category:  

Alkaloids Piperidine Alkaloids Liliaceae Plants Fritillaria ussuriensis Maxim. Disease Research Fields Inflammation/Immunology

Target:  

mAChR Angiotensin-converting Enzyme (ACE) Apoptosis

Peimisine (Ebeiensine) hydrochloride is a muscarinic M receptor antagonist and angiotensin converting enzyme (ACE) inhibitor. Peimisine hydrochloride shows anti-tumor, anti-inflammatory, antihypertensive activities. Peimisine can induce apoptosis and be used in cough and asthma research .
3
DX600
DX600
0 Images
3 Cited Publications
Cat. No.: HY-P2222
CAS No.: 478188-26-0
Target:  

Angiotensin-converting Enzyme (ACE)

연구분야:  

Cardiovascular Disease

DX600 is a selective ACE2 specific inhibitor (KD: 1.3 nM), and does not cross-react with ACE. DX600 exacerbates diabetes-induced cardiovascular dysfunction and the increase in cardiac and renal NOX activity .
Assay Types